Cancer cells learn new ways and early aging lies in the DNA.
The basis for the study was a case of leukemia transmission from a pregnant mother to her unborn child. There are only 17 such cases in the world, but doctors found it necessary to study this situation.
As part of the study, an international team of scientists studied the mechanism by which such an infection could occur. Doctors have previously proven that in the vast majority of cases, cancer cells are blocked by the placenta or destroyed by the embryo's immune system. However, doctors found that the mutated cancer cells, which already lack the so-called tissue compatibility gene, were not recognized by the immune system of both mother and child. The tissue compatibility gene allows the human immune system to recognize foreign bodies and cells and destroy them or simply reject them.
Now scientists face an important task – to develop a tool that would detect cancer cells without this very gene, which are "invisible" to the immune system.
Early aging lies in the DNA
It was discovered which segment of DNA is responsible for increasing the biological age of a person. The open segment leads to a significant increase in biological age compared to the real one: the difference can be up to 4 years.
The new study, unlike previous similar studies in search of the "aging gene," was conducted on the basis of blood samples from three thousand people. Previously, all such studies were conducted on fruit flies, as well as mice.
Measuring a person's biological age became possible after the discovery, which was recognized as worthy of the 2009 Nobel Prize in Medicine. The discovery consisted in the isolation of protein components located at the ends of chromosomes – telomeres. The larger the telomeres, the more reliably the chromosome is protected, but over the course of life, the telomeres are damaged and shortened. Thus, it is possible to calculate the biological age of a person.
During the study, a large amount of DNA obtained from human blood was analyzed, and the researchers were able to identify a segment of DNA that determines the rate of telomere division.
In the future, the results of this study can be used to prolong human life by at least 3-4 years. And this will also help to get rid of age-related changes that often affect humans. كود برومو 1xbet اليوم